Located on U.S. Highway 24 in eastern Pottawatomie County, St. Marys is the fastest growing incorporated city in Pottawatomie County. From St. Marys it is 30 minutes to both Manhattan and Topeka.
Custom Wood Products, Patriot Outfitters, Florence Adams, Nemaha County Coop, and KG Moats and Sons are a few of the major employers. These locally owned businesses are nationally known and the city's growth and location positions itself well to be home to additional business startups, expansions, and relocations.
St. Marys is located on the historic Oregon Trail.
City of the 3rd Class Commission/Manager form of government